Quick Links
Scouting and synthesizing monsters are huge parts of playingDragon Quest Monsters: The Dark Prince. You’ll want to do it not only so you can continue getting stronger but also because it is exciting to see and unlock all the monsters you can’t find by just exploring the world.
Many of these monsters are some of the strongest the game has to offer and come with the best skills, high stats, and powerful talents. Some of them might even be familiar if you’ve played other Dragon Quest games before.

How To Do A 4-Monster Synthesis Combination
Forseveralof theunique synthesis combinations, as well as ahandful of non-unique combinations, you’ll need tocreate a specific chaincalled afour-monster synthesis combination.
A four-monster synthesis combination is created bycombining a set of four monstersintoany resulting monsterwhileensuring that the four monstersneeded for the monstermake up the grandparentsof both offspring.

For example, tocreate a Buntzenburner, you’ll needfour monsters: aDancing Flame, aFrostburn, aSoulspawn, and aBrimstone Bulb.
List Of All Unique Synthesis Combinations
Whilesome are found in regular familieslike Dragon,mostof theunique synthesis combinationsin The Dark Prince can befound in the ??? Family.
This family is primarily made up ofantagonists from other Dragon Quest games, such asJasper UnboundandDhoulmagus, as well as somestory-significant supporting characters, likeRamia.

X Rank Unique Synthesis Combinations
All X-Rankunique synthesis combinationshave their own unique Talent, which can befurther passed onto other monstersregardless of the offspring’s rank.
Most X-Rank monstersrequire at least one other unique synthesis combinationto create them.

133
134

Lord of the Dragovians
519
???
Estark
4-Monster Synthesis
Rhapthorne x Psaro the Manslayer x Nimzel x Nelgel The Netherfiend
520
521
522
Nokturnus
Lord of the Dragovians x Mortamor x The Almighty x Ramia
523
Xenlon x Phoenix x Great Keeper x Fluffy
S Rank Unique Synthesis Combinations
Similar to most X Rank monsters, amajority of the S Rank unique synthesis combinationsalsorequire other unique combination results, and you’ll need to create large synthesis chains to obtain them.
63
128
129
130
131
132
203
204
278
Rug Cutter
King Jester Slime x Queen Slime x Splatypunk x Greater Platypunk
351
426
427
496
500
501
Orgodemir
Night Knight x Macho Picchu x The Time Being x Pandora’s Box
502
503
504
505
506
507
508
509
510
511
513
514
515
516
517
518
Grandpa Slime x Snipevine
Other Unique Synthesis Combinations
Outside those in S and X Rank, ahandful of unique synthesis combinationsexist in thelower ranks, withtwo of them being antagonist monstersand the othertwo being special 4-Monster synthesis combinations.
337
339
490
498
499